In the simulation, it will be considered whether it would have been possible for the Persians, at least, to obtain a Pyrrhic victory over the Macedonians, forcing Alexander to rethink or postpone his military strategy. To this end, in operational strategy the Persian device for approaching the battle would be more expectant, reacting to Macedonian movements as needed. In tactics, the maneuver would be that of an elastic defense, initiating actions by a light cavalry line on the riverbank - rather than the entire cavalry - acting as a covering force; in a second line, the center would be kept strong in heavy infantry, around which the light infantry and cavalry forces would make combined counterattacks of destruction and / or rampant. The decisive moment for the concentration of the maximum combat power would be in the place and in the period of performance of Alexandre himself.