Mesothelioma is a form of cancer that is becoming more and more common. The most common cause of this cancer is exposure to asbestos. When constantly exposed within sufficient protection, asbestos dust and fibres affect the mesothelial cells which make up the mesothelium. Treatment of recurrent malignant mesothelioma may be one of the following: Surgery to remove part of the chest wall.Chemotherapy, if it was not given as initial treatment.A clinical trial of immunotherapy.A clinical trial of targeted therapy. A clinical trial of chemotherapy. A clinical trial of surgery.